The Kielb Research Lab

Welcome to the BioSpectroElectrochemistry Group located at the Institute of Physical and Theoretical Chemistry at the University of Bonn. We are part of the Transdisciplinary Research Area “Building Blocks and Fundamental Interactions of Matter” (TRA Matter).

Research Focus

We aim at exploring how nature performs complicated redox reactions constituting key processes in the environment and life, like biomass degradation and or cellular respiration. At the heart of such processes are often redox biocatalytic metalloproteins which present the main inspiration for our mechanistic investigations. In our research mission, we want to understand how we can harness and further engineer the unrivaled efficiency of such natural biological systems towards the development of artificial biohybrid systems applicable in bioelectronic devices.

Methodologically, we employ the combination of experimental techniques including advanced Raman spectroscopy, electrochemistry, and protein engineering. Specifically, surface-enhanced resonance Raman spectro-electrochemistry allows us to correlate the structural information of the molecule interfaced on electrodes with its redox functionality. Check out our Research to get to know more about our current projects.

Press release about our start at the University of Bonn:


Funding

News

25-27.03.24 Patrycja attended Bunsen Tagung in Aachen and gave a talk.

16.11.23 Our collaborative work with the group of Barbara Kirchner (Uni Bonn) has been published in the ACS Journal of Physical Chemistry Letters: https://doi.org/10.1021/acs.jpclett.3c02761.

30.10.23 Patrycja gave a ‘kick-off’ lecture at the GDCh Kolloquium at Uni Bonn

27.08.23 Patrycja attended International Conference on Advanced Vibrational Spectroscopy (ICAVS12) in Krakow, Poland, and gave an invited talk.

31.07.23 Michelle and Hendrik joined EBSA Congress on Biophysics in Stockholm and presented posters with their projects. Congratulations to Michelle, who received a Travel Grant from the German Biophysics Society!

21.06.23 Our first publication from the lab is now online: ‘Cyclic voltammetry, square wave voltammetry or electrochemical impedance spectroscopy? Interrogating electrochemical approaches for the determination of electron transfer rates of immobilized redox proteins’ BBA Advances https://doi.org/10.1016/j.bbadva.2023.100095

05.05.2023 We received an INNOVATION Grant funded by TRA Matter to start the collaborative project with JProf. Dr. Ala Bunescu (Uni Bonn, Organic Chemistry) and Dr. Luke Wylie (Uni Bonn, Theoretical Chemistry). We search for an interested PhD student to commence the project.

25.11.22 DAAD PROCOPE project in collaboration with Dr. Alexandre Ciaccafava for 2023-2024 has been funded.

23.11.22 Patrycja visited HITS Institute in Heidelberg and gave an invited talk in the Group of Prof. Frauke Gräter. Thank you for the invitation and great discussions!

11.11.22 Aina submitted her Bachelor Thesis!

18.10.22 Patrycja gave an invited GDCh Colloquium talk at the University of Cologne.

03.10.22 The publication on ‘Does Tyrosine Protect S. Coelicolor Laccase from Oxidative Degradation or Act as an Extended Catalytic Site’ is published online in the ACS J. Phys. Chem. B https://pubs.acs.org/doi/full/10.1021/acs.jpcb.2c04835

23.09.22 The funding for Confocal Raman Spectrometer equipped with 5 laser lines is granted by the DFG Major Research Instrumentation Grant

25-28.09.22 We (Michelle, Hendrik, Patrycja) are at the German Biophysical Society Meeting in Konstanz

16.09.22 Carla submitted her Bachelor Thesis!

07-09.09.22 We (Michelle, Hendrik, Patrycja) are at the German Physical Chemistry Society (Bunsen) Meeting in Giessen

15-22.07.22 Patrycja is at the European Bioinorganic Chemistry Conference in Grenoble, France

06.06.22 Patrycja visited the Chemistry Department and School of Biophysics at the University of St. Andrews

31.05.22 Patrycja gave a Welcome Lecture Talk at the TRA Matter Colloquium

01.10.21 The journey at the Uni Bonn begins!